Expresión de búsqueda: CYTOCHROME P-450 CYP1B1 
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Descriptor Inglés:   Cytochrome P-450 CYP1B1 
Descriptor Español:   Citocromo P-450 CYP1B1 
Descriptor Portugués:   Citocromo P-450 CYP1B1 
Categoría:   D08.244.453.040.500
D08.811.682.690.708.170.040.500
D12.776.422.220.453.040.500
Definición Inglés:   A cytochrome P450 aryl hydrocarbon hydroxylase that has specificity for ESTROGENS which it converts into 4-hydroxy estrogens. CYP1B1 has been shown to be physiologically important for FETAL DEVELOPMENT with mutations in the CYP1B1 gene resulting in congenital forms of GLAUCOMA and Peter's anomaly. 
Nota de Indización Inglés:   /antag: coordinate with CYTOCHROME P-450 ENZYME INHIBITORS
Nota Histórica Inglés:   2015 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   55605 
Identificador Único:   D065633 

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